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Registered Nurse Salary in St. Louis, MO

Updated

The median registered nurse in the St. Louis area earns $83,180 a year ($39.99 an hour), 15% below the U.S. median ($97,550) and 2% above the Missouri median ($81,780). Half of the 35,200 registered nurses there earn between $77,410 and $100,230.

Percentiles. Dark: the middle half of earners. Red line: median. Dashed: U.S. median.
Registered Nurses, May 2025 (latest official data). Metro area: St. Louis, MO-IL.
Annual paySt. Louis areaMissouriU.S.
10th percentile$63,440$63,230$68,940
25th percentile$77,410$76,050$80,330
Median$83,180$81,780$97,550
75th percentile$100,230$98,560$112,350
90th percentile$104,460$104,390$137,470
Average$88,310$85,900$101,420
Jobs35,20076,3103,379,720

St. Louis, MO ranks 45th of the 50 largest U.S. metro areas for registered nurse pay. Highest: San Jose, CA ($216,740).

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Sources

U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, www.bls.gov/oes. BLS.gov cannot vouch for the data or analyses derived from these data after the data have been retrieved from BLS.gov.