Nurse Practitioner Salary in St. Louis, MO
Updated
The median nurse practitioner in the St. Louis area earns $131,580 a year ($63.26 an hour), 1% below the U.S. median ($132,300) and 1% above the Missouri median ($129,930). Half of the 3,430 nurse practitioners there earn between $127,460 and $154,500.
| Annual pay | St. Louis area | Missouri | U.S. |
|---|---|---|---|
| 10th percentile | $108,340 | $100,650 | $101,340 |
| 25th percentile | $127,460 | $119,910 | $117,990 |
| Median | $131,580 | $129,930 | $132,300 |
| 75th percentile | $154,500 | $144,640 | $156,700 |
| 90th percentile | $164,280 | $162,060 | $174,420 |
| Average | $135,550 | $130,970 | $137,300 |
| Jobs | 3,430 | 7,710 | 323,040 |
St. Louis, MO ranks 29th of the 50 largest U.S. metro areas for nurse practitioner pay. Highest: San Jose, CA ($231,560).
Paid less than $131,580? That gap, with its source, is the strongest line in a raise request. Check your pay for your level in 30 seconds. Free, no sign-up.
Check my payNurse practitioner pay in other cities
- Kansas City, MO: $130,760
- San Jose, CA: $231,560
- San Francisco, CA: $219,080
- Sacramento, CA: $172,010
- Riverside, CA: $169,920
- San Diego, CA: $163,860
- New York, NY: $163,340
- Los Angeles, CA: $161,470
- All cities
Similar jobs in St. Louis, MO
- Registered Nurse: $83,180
- Pharmacist: $138,530
- Physical Therapist: $100,600
- Dental Hygienist: $97,650
- Speech-Language Pathologist: $86,480
- Occupational Therapist: $95,770
- All jobs in St. Louis, MO
Sources
- U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, published May 15, 2026
U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, www.bls.gov/oes. BLS.gov cannot vouch for the data or analyses derived from these data after the data have been retrieved from BLS.gov.